In the context of better-controlled systemic disease as new therapeutics, advanced imaging, and improved screening have led to lengthened survival, brain metastases are emerging as a new challenge being a major limitation of life expectancy and quality of life.


The use of Stereotactic radiosurgery for the treatment of brain metastases is increasing. Fractionated whole brain radiotherapy (WBRT) has been a standard treatment of cerebral metastases, but provides limited local tumour control and often unsatisfactory clinical results. SRS offers advantages with high local efficacy, preservation of cerebral functions, longer survival rates, short hospitalisation and the option to continue systemic chemotherapy

A recently published article finds the use of SRS for Non-small cell lung cancer brain metastases has steadily increased over time in the United States, As this study shows, the use of stereotactic radiosurgery to treat brain metastases continues to rise, but there are still wide disparities in treatment choice when comparing SRS vs. WBRT. including in the UK. Still, Gamma Knife was found to be the most commonly used modality for SRS in the USA.